
Professional Guidelines Included
Learn the Total knee replacement: PFC replacement (De Puy-Synthes) surgical technique with step by step instructions on OrthOracle. Our e-learning platform contains high resolution images and a certified CME of the Total knee replacement: PFC replacement (De Puy-Synthes) surgical procedure.
There are two principle designs of the PFC, a posterior cruciate sacrificing (PS) and an cruciate retaining (CR) PFC knee. The PS design incorporates a polyethylene intercondylar post which compensates for the resected posterior cruciate ligament. This post engages the corresponding femoral component receptacle enabling roll back.
The PFC design was first released in 1996, nearly 1/3 of a million have been implanted. It has a 3.58% cumulative percentage probability of a first revision at 15 years recorded on the NJR, which clearly supports its use. The kit to insert it, is as you will see, is straightforward and the implant has predictable outcomes; features beneficial to both patient and surgeon. This is why I use it.
There are many implant designs on the market, each purporting to be the best. Some incorporate differing radius of femoral curvature, others low contact stresses, others have rotating platforms, others a medial pivot. In my opinion though outcome is as dependant on soft tissue handling, an understanding of knee biomechanics & intra-operative balancing and pre and post operative rehabilitation.
This technique details the posterior cruciate sacrificing PFC (Depuy) total knee replacement.

INDICATIONS
End stage arthritis of the knee, particularly osteoarthritis of two compartments, fixed significant valgus / varus deformities or inflammatory arthritis.
SYMPTOMS & EXAMINATION
Patients will classically present with a ‘deep’ knee pain which is progressive, affecting ADLs and becoming unresponsive to simple oral analgesics. Some patients are able to localise the pain very specifically whereas others may describe a more diffuse anterior knee pain. Pain is worse with activity and eases with rest.
The knee may feel stiff and patients may describe giving way which may be secondary to mechanical defects or pain inhibition.
Clinical examination will reveal diffuse pain at the level of the joint line (usually anterior). Posterior or posteromedial / posterolateral tenderness is uncommon. Patients may have an effusion.
It is important do check for a passive and active range of movement and to document any fixed flexion deformities. The presence of valgus or varus deformities and whether they correct or not is also imperative.
Alway check the neurovascular status, the distal skin condition and examine the hip for referred pain.
IMAGING
Simple AP standing, lateral and skyline view are required. I do not routinely perform alignment views unless a clinical deformity is noted.
ALTERNATIVE OPERATIVE TREATMENT
For a patient with failed conservative measures and osteoarthritis in greater than one compartment or inflammatory arthritis there is little alternative operative treatment. OA in a single compartment can be treated with a unicompartment knee replacement, a high tibial osteotomy or a patellofemoral replacement.
NON-OPERATIVE MANAGEMENT
This should always be attempted before undertaking a TKA. Physiotherapy, oral analgesia, walking aids and braces may help during the early stages of arthritis. It is not uncommon that weight loss in the obese patient improves symptoms, challenging the patient regarding this can be difficult but should be undertaken.
CONTRAINDICATIONS
A medically unfit patient.
Ongoing acute or chronic infection.
Poor tissues locally at the knee or distally around the ankle / foot. Open ulcers should be treated. I would always consider a vascular referral for the arteriopath.
Finally some patients present late, they may have significant fixed valgus / varus deformities or have bone ‘through’ bone disease. Augments and stems can be used with the PFC but in cases with severe bone defects I would consider revision type implants. Likewise for a significantly fixed valgus knee a more constrained design would potentially be more appropriate.

There is comparatively limited equipment required. There are however two types of kit to aid insertion, the High Performance (not shown) and the Specialist 2 (detailed). IM referencing of using the tibia is an option with both systems.
Confirm the x-rays are up to date. OPD ROM has been documented.
Confirm the skin is healthy with no infections / bites / blisters / ulcers.
Shaving is performed where necessary in the anesthetic room
We use teicoplanin and gentamycin as antibiotic prophylaxis
Tranexamic acid (1g IV) is used immediately prior to release of tourniquet and not pre-op.

There are not special precautions.
Patients can mobilise the same day if able.
Patients are immediately full weight bearing.
X-ray can be completed once the patient is more comfortable.
Bloods (FBC and U&E) at 24 hours. If Hb is satisfactory patients do not not repeat at 72 hours if still an inpatient.
Thromobprophylaxis (NICE)
Patient attend daily physiotherapy and then OPD group physiotherapy and are reviewed in the OPD at 8 weeks. I would expect patients to have obtained 0-120 degrees of motion by 8 weeks.
We are fortunate to have an Advanced Nurse Practitioner who is able to field calls from patients once discharged. We have a very low threshold and will bring patients back for review if they have concerns regarding their wound. Fortunately our infection rate is low (0.4% for primary knees).

Preservation vs. resection of the infrapatellar fat pad during total knee arthroplasty Pt II. A systematic review of published evidence. Nisar. Lamb, Somashekar, Pandit and van Duren Knee 2019 26(2):422-426
Mechanical, anatomical and kinematic axis in TKA: Concepts and Practical Applications. Cherian, Kapadia, Banerjee, Jauregui, Issa, and Mont. Curr Rev Musculoskelet Med. 2014 Jun; 7(2): 89–95
Cementing technique for primary arthroplasty: a scoping review. Refsum Nguyen, Gjertsen, Espehaug, Fenstad, Lein, Ellison, Høl and Furnes. Acta Orthopaedica 2019 2019 Aug 27:1-8
Comparison of cruciate sacrificing and cruiate retaining PFC signma total knee replacement: 683 knees minimum tow year follow-up. Blyth, Stother, May, Leach, Crawfurd, Brown, James, Tarpey. JBJS (Br) 2012;94(supIX):3
As mentioned earlier cumulative percentage probability of a first revision at 15 years for the PFC 3.58. When separating out PS vs CR the PS does slightly worse at 4.28 versus 3.18. However this is not statistically significant (95% CI overlap), nor do these raw data points account for any confounding variables.
NJR data would also not necessarily support the notion that a rotating type platform is superior either.
The NJR have released PROMS data nationally, for units and individual surgeons. Patient reported data is always very powerful. I will report on outcome nationally but for the record my data parallels national average! There is one major discrepancy insomuch as I note that my ASA3+ population is double the national average. I need to move to healthier place.
Nationally questionnaires are distributed six months post-operatively.
Success is measured by asking about general health. The question posed is; Overall, how are your problems now, compared to before your operation? 2.3% of patients are much worse, 3.5% are a little worse 4.6% are about the same with 16.4% a little better and 73.2% much better.
Satisfaction is measured by asking the question; How would you describe the results of your operation? 3.3% report poor, 11.2% fair, 24.7% good, 35.7% very good and 25.1% excellent.
Compared to total hip arthroplasty where the combined score of much worse and a little worse is 2.2% and poor or fair satisfaction scores are 7.3% there is clearly a long way to go.
Reference
- orthoracle.com















































































