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Ankle arthrodesis (fusion)- Trans-fibular approach

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An open ankle fusion is a relatively straight-forward operation which in appropriate patients is transformatory (both in terms of pain reduction and function).
The risk associated is in practical terms “front loaded” and relates mainly to non-union.
Late onset subtalar and midfoot arthritis is likely as a radiographic phenomenon, though not likely to require later surgery.
There are a number of different techniques described to perform the operation. Which one is chosen is less relevant than ensuring a correct and functional alignment is achieved intra-operatively with appropriate joint surface preparation and that the compensatory joints (subtalar and midfoot) are free of significant arthritic change and asymptomatic.
A sound ankle fusion is entirely compatible with heavy manual work


INDICATIONS.
–Isolated Ankle arthritis: One can argue fusion vs replacement for a while and the when that’s finished start on open vs arthroscopic fusion. A fusion in general is for higher demand/ younger patients or any patients wishing a greater degree of predictability than afforded by Ankle replacement. With a fusion the “risk” in the majority of patients can be regarded as “front-loaded”. As long as a non-union does not occur (5-10% chance, technique dependent) then in the majority no later intervention is likely though the subtalar and midfoot joints are highly likely to become degenerate. Function will reduce with this if this occurs but the lead time is likely to be 10-20 years. With an ankle replacement the failure rate of most implants (which have been in use for long enough) is 2%/annum which equates to a 10 year survivorship of 80% .
-Ankle arthritis with fixed deformity : Any fixed deformity one is not confidant in being able to correct arthroscopically is better done with an open fusion which is a much more straight-forward task. There is no issue with the degree of deformity but one should claerly identify the level of deformity and which joints are contributing to it.
-Revision Ankle Fusion: Consider as an alternative to double (Ankle & Subtalar) fusion.
SYMPTOMS & EXAMINATION:
Most patients with severe ankle arthritis localise the pain well to the level of the joint. Very much as with arthritis elsewhere symptoms tend to progress from early activity /start up pain which eases off through to progressively more disabling and continual weight bearing pain and on occasion as far as pain at night or at rest. A much less common symptom which can co-exist with pain is that of ankle instability. If gait is becoming altered due to the arthritis pain proximal to the ankle may occur secondary to alteration of the weight-bearing axis of the limb.
The vast majority of patients will either have a history of a significant injury (such as an ankle fracture), chronic deformity (for example Cavo-varus) or a past history of chronic lateral ligament instability. More rarely the cause is a more generalised tendency to osteoarthritis or an inflammatory arthropathy.
On examination swelling and tenderness well localised to the ankle is common. Range of movement is often reduced and may be uncomfortable. More important than ankle movement is what the subtalar and midfoot mobility is like. If both are very mobile then it is likely that post-fusion good compensatory movement in these joints will allow normal gait and in fitter, younger patients even the ability to return to running. Conversely if movement here is restricted these joints should be carefully inspected with CT to confirm or refute additional arthritic change. If still equivocal then an injection into the ankle joint with inta-articular contrast (see below).
Any deformity should be noted. Varus is most common and valgus and equinus least common. The key issues with any deformity are A:Whether it is passively correctable (or not) and B.:Being sure of its anatomical location(s). The former is easily clinically determined .The latter can be more difficult to be sure on , in particular in the presence of severe deformity and CT is indicated for this.
In assessing equinus it should be appreciated at what level(s) the deformity rests. Beware of associated fixed midfoot equinus which will leave the mid/forefoot in a plantar flexed position once the ankle is fused in neutral if it is ignored. A midpoint plantar fascia release may be required to place the foot in a functional position post-operatively. If dealing with isolated ankle equinus be prepared to add a triple cut (or open )Achilles release dependent on the severity of the deformity. With an open ankle fusion given that more bone is resected often enough laxity is created in the soft tissue envelope simply by the bone preparation.
The rest of the lower limbs alignment should not be forgotten. In general correction of deformity should start proximally and proceed distally.
A vascular examination must be made and if abnormal dealt with appropriately.
INVESTIGATION:
Plain X-Ray: This is the initial imaging for most patients with ankle arthritis of any degree. Though the ankle is relatively well visualised (and the films should be taken weight-bearing) the subtalar and midfoot joints aren’t so well shown , in particular in the presence of associated deformity through the area.
CT scan. This is better in defining how much relevant arthritic change exists and where it is than MRI. It is also easier to differentiate the level of deformity from CT than MRI. There are cases where significant cystic change exists and will require bone grafting.Its location and extent is again best defined with CT.
MRI scan: An MRI is more sensitive for early degenerative change but will be degraded by any internal fixation and is not 100% sensitive for early arthritis. It can be more difficult to be objective about the severity of more advanced arthritic change as bone oedema ( a reversible phenomenum) complicates the MRI images. A CT lacks this sensitivity which is a positive and not a negative. Some surgeons prefer MRI to CT in assessing a joint pre-fusion.
X-Ray guided injection: This should be into whichever joint (ankle or subtalar ) appears more likely the location of symptoms. Contrast is needed as in a proportion of patients the two joints will inter-connect and improvement of symptoms after injection into one cannot under these circumstances be regarded as discriminatory.
ALTERNATE OPERATIVE MANAGEMENT:
Arthroscopic Ankle fusion.
Arthroscopic Ankle debridement.
Ankle replacement.
Distal Tibial Osteotomy.
Technique variations for open fusion: Anterior ,medial and posterior approaches all have their advocates. Fixation can also be by compressive plate, or external frame.
NON-OPERATIVE MANAGEMENT:
Activity modification and analgesia.
Local anesthetic & steroid injection.
Orthotics & Shoewear modifications.
CONTRAINDICATIONS:
Active infection , active smoking ,poor vascular inflow, poor soft tissues : require correction before fusion is considered. All patients need to undertake to be non-smoking post operatively and until confirmation that the ankle has unequivocally united.
Steroid and immuno-suppressive medications: Dosages will require minimising pre and post-operatively
Subtalar/midfoot arthritis: If the subtalar and midfoot joints are effected by anything more than minor and asymptomatic arthritic change then one should consider either an ankle replacement , double fusion (Ankle & subtalar) or true Pan-Talar fusion.
Poor patient compliance or understanding. As important as any of the other contraindications.

GA or regional anaesthesia
Femoral & sciatic blocks for post-operative pain relief
Laminar flow , peri-operative antibiotics , 2-4 weeks of post operative LMW Heparin
Thigh tourniquet and Flowtron on contra-lateral calf
Ankle positioned into neutral using sandbags & side supports
Large , rolled up sterile towels behind the ankle to improve access for cuts.

The approach shown is a trans-fibular one. The skin incision should be in the mid-line of the fibula. For an ankle fusion it extends a generous hands breadth above the ankle and inferiorly runs down past the fibula tip to the proximal end of the sinus tarsi.

An initial limited fine-scissors dissection through the fat layer(2), just in the line of the skin incision, is undertaken to avoid cutaneous nerves. These are the superficial peroneal nerve anteriorly and the sural nerve posteriorly.
This initial scissors fat dissection is followed by a knife dissection down to identify the fibula(1) in the same line with a knife.

An extensive fibula sub-periosteal dissection is required for ankle fusion. Posteriorly the peroneal tendons should be seen and avoided. Anteriorly the lateral edge of the tibia should be identified sub-periosteally by direct dissection across from the Fibula. Inferiorly the fibula tip should be identified, though doesn’t need to be much dissected beneath.

The soft tissues are protected with Trethowans retractors(1) prior to excision of the Fibula.
A large single sided reciprocating saw blade is used to obliquely cut the fibula at approximately a hands breadth above the ankle to allow access to the ankle joint.
Care needs to be taken not to notch the Tibia or cut the peroneal tendons by too aggressive sawmanship at this stage.

Once the fibula is divided proximally it needs to be removed, or reflected, to give access to the ankle. It has numerous strong soft tissue restraints all of which will need to be sharp dissected off it to allow its mobilisation.

The fibula soft tissue attachments which will need to be divided are the interosseous membrane, anterior and posterior Tibio-fibula ligaments, Anterior talo-fibular ligament and the calcaneo-fibular ligament.
As long as all the soft tissue attachments to the fibula are sectioned as close to the fibula as possible then these structures do not need to be individually identified.
Here an osteotome is being used to place soft tissues under tension during division. A large bone holding forceps is helpful for this too to allow traction upon the fibula.
An alternative method of dealing with the fibula through this approach(not shown) is to leave as much of its posterior soft tissue directly attached as possible. The anterior tissues are sectioned as shown to allow it to be swung posteriorly during the joint preparation. At the end of the ankle fusion it is then fixed back onto the tibia and lateral talus as a vascularised graft. Prior to this the medial cortical bone of the Fibula is removed with a saw as is the lateral talar cortical bone.
Following this the fibula is fixed with several long small fragment screws to the lateral aspect of the talus and tibia.

A large bone holding forceps (know as “Lions’ tooth” forceps) is needed for manouvering the fibula(1) as its’ soft tissues are progressively divided.
Care should be taken to avoid dividing the peroneal(2) tendons posteriorly.
Once the lateral talus(4), tibial incisura(3) and antero-lateral tibia (5) are identified preparation for ankle fusion can progress.

The anterolateral edge of the tibia is addressed with sharp sub-periosteal dissection. The aim is to produce a good continuous soft tissue sleeve from antero-lateral joint to the medial aspect of the joint. This sharp dissection to expose the distal tibia need only proceed a few cm before it can be completed using a large “round-nosed” periosteal elevator.

To further expose the tibia the round-nosed periosteal elevator is used to strip across to the medial malleolus. Distally some sharp dissection of the soft tissues off the lateral talus is also required , usually down to the level of the Talar neck.

The next step in every case is an exposure of the medial joint line and medial Malleolus(2). A longitudinal skin incision is used , skirting the medial aspect of Tibialis anterior. The medial Malleolus (2) should be exposed by sub-periosteal dissection and its width noted.
An initial vertical cut should be made with a fine power saw a few mm medial to the junction of the Malleolus and Tibial plafond. More width may need to be taken if the Malleolus has become hypertrophied. The vertical extent of this cut is used to mark the depth of tibial plafond that will be removed (3). This picture shows the transverse cut used to remove the distal Tibial articular surface (4) has already been made. This actually occurs in the next step of the operation.
The objective is to remove enough distal tibial articular surface but not to fracture the medial Malleolus. The Malleolus provides stability during fixation and a sound “buttress” for fixation. If the Malleolus fractures it is not the end of the world. The whole construct will be less stable during fixation and there will be less of an anatomical guide as to how to place the ankle so care should be taken when both positioning and when fixing.
With a very severe fixed varus deformity of the ankle it may on occasion be necessary to excise the Malleolus to get a complete correction of the deformity.
The tip of the long reciprocating blade is aimed from its point of lateral joint insertion to the top of the vertical medial Malleolar bone cut. An assistant is needed with direct visualisation of this medial point to ensure during cutting that the cut bone marker is not over or under shot.

A lateral X-ray of a different type of open fusion where the fibula is decorticated and applied as a vascularised strut graft across the ankle (known in the UK as an RAF fusion).
It is worthy of inclusion as it demonstrates established subtalar and talo-navicular arthritis that has presented circa twenty years following an ankle fusion. Only orthotic management was required.

The postero-lateral edge of the tibia (2) should be defined by careful sharp sub-periosteal and blunt elevator (1) dissection as here. The clear definition of the posterior extent of the Tibia assists in the safe completion of the posterior aspect of the tibial articular surface bone cut.

A large single edged reciprocating saw blade is used to remove the distal tibial articular surface .
Before deciding on how much Tibia to remove any anterior osteophytes should be removed as these will just confuse the assessment.
The amount to be removed is variable and often a balance needs to be struck. If on every occasion the bone is cut back so that only healthy sub-chondral bone remains there will be cases where significant tibial length is lost. A more immediate problem than the limb shortening this produces will be that this will cause the flared inferior & medial Talus to impinge on the medial malleolus and not compress against the Tibia if too much shortening occurs.
A good example of when not to cut back to the most proximal extent of poor bone is shown in the imaging section at the end. Such deep cystic areas of arthritis can simply be curetted out , drilled into and packed with graft. The bone cut of course needs to be properly aligned.
The plane of this cut needs to be at 90 degrees to the long axis of the tibia which is judged visually by reference to the anterior Tibial crest. The tip of the blade is slid all the way across to the vertical cut in the medial Malleolus

A CT scan showing the shape of the posterior aspect of the tibia (3), the Fibula(1) and anterior tibia (2). This should be studied. There is less depth of bone postero-medially than postero-laterally .
Therefore if resecting the distal tibial articular surface using lateral access (as in this technique) the tip of the saw blade needs to be angled anteriorly after the postero-medial cortex has been cut to avoid penetrating the postero-medial soft tissues which is a bad idea. The most posterior aspect of the cut can also be completed using a large Hibs osteotome in a controlled fashion.

To ensure adequate visualisation for the distal tibial cut a large bone lever (2) is used to elevate the anterior soft tissue envelope. The cut needs to be at 90 degrees to the long axis of the tibia in both sagittal and coronal planes. With bony deformity this will result in the removal of a “wedge” shape of articular surface
The objective of the cuts is to place the ankle fusion in a functional position. Simply put (which is all that is required) in the vast majority of cases the foot should be squarely beneath the Tibia in the coronal plane and at right-angles to the Tibia in the sagittal plane. Good luck with adding in the 5-10 degrees of valgus mentioned in most publications!.
Varus, valgus and equinus need to be corrected. As mentioned in the Indications section there needs to be a pre-op identification of what level these deformities may lie at.
The amount of bone resected with appropriately angled bone cuts in an open ankle fusion allows easy correction of most ankle deformity.

Care needs to be taken with the posterior extent of the distal tibial cut. The large periosteal elevator (1) can be placed behind the posterior border of the tibia as a guide and care should be taken not to over shoot the posterior cortex. Care should also be taken re the angulation of the tip of the saw blade given that there is less postero-medial tibial depth. Angle the blade anteriorly and withdraw the blade laterally once the medial deep cut has been completed or is almost completed.

The distal tibia is removed sometimes in a single piece as here. A sharp Hibs osteotome can be useful to run through the saw cuts before attempting mobilisation.
Posterior soft tissue attachments will still be present and these will need to be sharp dissected off as the articular surface is delivered out under traction using a Kochers’ forceps during the ankle fusion.

The talar dome(2) is placed opposed to the cut tibia(1) so that the foot sits at ninty degrees to the long axis of the tibia in the saggital plane .In the frontal plane the centre of the patella is aligned with the 2/3 metatarsals .This should allow an appropriate position for the talar cut.
The cut is made with a broad oscillating blade , though the large reciprocating blade can be utilised with practice for this.

Once the Tibial cut is correct the talus is simply cut
parallel to the Tibia(1). This is best done with a long and relatively thin oscillating blade. After resection of the Talar dome one should ensure that there are no irregularities on the dorsal Talar surface which will compromise the bone to bone contact of Tibia and Talus.

In cases of arthritis (osteo or inflammatory) where there is extensive cystic change effecting the articular surfaces resecting to the base of the deepest defect can result in the removal of too much bone. The effects of this can be unnecessary shortening of the limb and more immediate problems with achieving good bone to bone contact .It may well be more appropriate to simply extensively drill into the deeper cysts and fill with bone graft .

After parallel tibial and talar resection the talus should easily be translatable proximally to make good contact with the tibia prior to fixation.
In non deformed ankles this is generally the case. In significant varus deformities(as with this case) the hypertrophied medial malleolus will often impinge upon the medial Talar body and provide a bony block to reduction.

To allow reduction several cms of medial malleolar tip will need to be removed. Alternatively(or sometimes additionally) the medial flare of the Talar body can impinge upon the tip of the medial Malleolus and this may need to be similarly removed. Either procedure is best done under direct vision using a Lambotts osteotome or oscillating saw with very small arc. The posterior cortex of the Malleolus overlies the Tibialis posterior tendon and is best divided only with an osteotome.

A Lambotts osteotome being used to lever off the medial malleolar tip(1) prior to ankle fixation.

The appearance of the medial Malleolus (2) after removal of the Malleolar tip (3). If this still does not allow congruent reduction of the ankle fusion then some of the medial wall of the talus (1) may need to be removed. Time must be spent achieving a stable and as near complete contact between the cut bone surfaces as possible.
In terms of fixation use big screws and as many as you can . This stage needs Image Intensification.
Before commencing fixing make sure that the joint is appropriately aligned (as described previously) and almost as importantly the bone to bone contact is excellent with the ankle appropriately positioned. 2 large diameter (2.4 mm +) wires should be placed initially away from the planned position of the definitive screws.
A good starting point for fixation is two short thread partially threaded large (6-5-8mm diameter) fragment cancellous screws. A cannulated screw system should be chosen otherwise getting the orientation of drill holes wrong results in large & unfilled holes being left in the bone. Place all guide wires for intended screws before commencing drilling. The initial 2 screws can be placed from the subcutaneous face of the tibia (avoiding both the thick anterior crest as well as being too posterior). A “spread” of their compressive effect should be aimed for by diverging the screws on both A-P and Lateral projections. The lateral Tibia can also be used for a third screw.
It is key that bone compression and stability is achieved. Use screws of as large a diameter as the bone will tolerate and with a good thread pitch (for example the Orthosolutions 8.0mm cannulated screws ). If with 2 screws the fix is not adequate keep increasing screw number (though it’s difficult to find room often for more than 3). Washers under the screw head may help the bone purchase (if they have been countersunk or are sinking into soft cortical bone). Rarely it may be necessary to have a screw with a longer thread which crosses the fusion site (thus negating its compressive effect) to improve stability .

2 weeks in back-slab
dressing changes at 1 & 2 weeks
Complete cast between weeks 2 to 6 & non-weight bear
Check X-ray at 6 week stage . Usually may commence light weight bear and progress to 50% body weight by 12 weeks. Dependent upon age , bone quality and co-morbidities, either week
6-12 is spent in a robust post-operative boot or in a walking cast. If grafting has been required then I will delay weight-bearing until 8-12 weeks depending on the extent of the grafting.
Further X-ray at 12 weeks . Satisfactory progression is judged by both radiographic progression as well as a patients comfort upon limited weight-bearing.
Generally a further 6 weeks is required at this stage in a post-operative boot.The progression from partial to full weight -bearing is made during this period assuming increasing function is comfortable.
A further X-ray is performed at 18 weeks to confirm union and if symptoms are in keeping with this the patient may move onto a stiff-soled hiking boot for a further 4 weeks , then normal shoes.
If there is equivocation about the state of union on X-Ray after 4 months consider CT.
If a patient is not improving clinically as per the protocol do not progress to the next level of function. This is to be monitored monthly clinically and by plain X-Ray. Key is that adequate immobilisation and reduction of loading is maintained until progress is definite. The early use of an external bone stimulating device should be considered.
No heavy manual type activity or sport for 5-6 months post operation.
A person with a mobile subtalar joint and midfoot will manage normal shoewear. Those with stiffer compensatory joints will required normal but stiffer soled shoes (or rarely boots).

Long term results following ankle arthrodesis for post traumatic arthritis.
L.M.Coester , C.L.Saltzman , J.Leupold, W.Pontarelli.
J Bone Joint Surg, 2001: 83-A:219-228
23 patients followed up 22 years following united ankle fusion(range 12-44 years). Outcome by self reported questionnaire & bilateral knee , ankle & foot Xray
91% incidence of radiographic subtalar Oa, no increased incidence of knee Oa , increased incidence First MTP Oa.
Functional limitations were common but the need for secondary operation was not.
Gait analysis and functional outcomes following ankle arthrodesis for isolated ankle arthritis.
R.T.Thomas , T.R.Daniels, K.Parker
J Bone Joint Surg, 2006:88-A:526-535.
26 patients , mean time after operation 44 months
5 patients noticed no gait abnormality , 12 patients felt improved with the use of orthotics
Differences in stride length & cadence on operated side , reduced movement all planes hind & midfoot.
Cigarette smoking and non-union after ankle arthrodesis.
Foot & Ankle.1994.15 (2);64-67.
T.K.Cobb , T.A. Gabrielsen , D.C.Campbell , S.L.Wallrichs , D.M.Ilstrup.
A very small but useful paper to quote to patients & inform your practice.
22 ankle non-union patients were case matched with 22 successful union patients.
10 of the non-union patients smoking at time of surgery versus 4 of the controls ( so it is possible to unite despite smoking , but perhaps keep that quiet).
A smokers risk of non-union after ankle fusion was calculated to be increased by 3.75 times.


Reference

  • orthoracle.com
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