
Professional Guidelines Included
Learn the Compartment fasciotomy and Hoffmann 3 spanning external fixator for open tibial fracture surgical technique with step by step instructions on OrthOracle. Our e-learning platform contains high resolution images and a certified CME of the Compartment fasciotomy and Hoffmann 3 spanning external fixator for open tibial fracture surgical procedure.
Open fractures of the tibia are the most common open long bone fracture with an annual incidence of 3.4 per 100,000 population. The mean patient age is 43 years however, the distribution is bimodal. They most frequently affect young adult males and elderly females. The usual mechanism is from high energy trauma such as a motor vehicle collision or a fall from significant height.
Open tibial fractures have been classified by Gustilo and Anderson in 1976 and subsequently revised in 1984. The fractures are first classified by the mechanism of injury – energy level. High energy injuries are automatically a type III. Type III is further subdivided into A, B and C.
Type I: Low energy; wound less than 1cm; clean; simple fracture pattern.
Type II: Low energy; wound greater than 1cm; soft tissue damage not extensive; no flaps or avulsions; simple fracture pattern.
Type III: High energy; extensive soft tissue damage; or multi-fragmentary fracture / segmental fracture / bone loss irrespective of soft tissue wound size; or severe crush injury; or vascular injury requiring repair; or severe contamination including farmyard injuries.
Type III has been subdivided into:
III-A: Adequate soft tissue to cover the bone.
III-B: Extensive soft tissue injury with periosteal stripping and bone exposure; major wound contamination.
III-C: Arterial injury requiring repair.
Importantly the Gustilo Anderson classification should only be determined after surgical debridement and must recognise the energy level from the mechanism of injury.
More recently the Ganga Hospital classification system has been developed in an effort to help better prognosticate between limb salvage or amputation. This system scores 3 criteria (skin, soft tissues, and skeletal damage) from 1 to 5 and also has additional risk factors (age > 65; contamination; chronic illness; systemic injury; other trauma – 2 points per additional risk factor). The score correlates with the recommended treatment and likely outcomes. It is most useful for Gustilo Anderson III-B injuries as this is a broad group. It has also shown greater sensitivity and specificity for predicting amputation compared to other severity scores. A score of 14 or less (out of 29) has shown good specificity and sensitivity for recommending limb salvage. A score of 17 or more has shown similar accuracy for predicting amputation.
Gustilo RB, Anderson JT. Prevention of infection in the treatment of one thousand and twenty-five open fractures of long bones: retrospective and prospective analyses. J Bone Joint Surg [Am] 1976; 58-A: 453-8.
Rajasekaran S. Ganga hospital open injury severity score – a score to prognosticate limb salvage and outcome measures in type IIIB open tibial fractures. Indian J Orthop 2005; 39: 4-15.
The principles for the management of open fractures have been agreed between the British Orthopaedic Association (BOA) and British Association of Plastic Reconstructive and Aesthetic Surgeons (BAPRAS). Their recommendations are available for download as a standard for trauma (BOAST). Here is a summary of the standards:
Patient’s with open fractures of long bones should be managed in a specialist centre that can provide combined OrthoPlastic care.
Antibiotics should be administered ideally within 1 hour of injury.
The injured limb should have regular / documented assessment of neurovascular status.
The limb should be realigned and splinted.
Continuous assessment to avoid compartment syndrome.
The wound should be photographed and covered with a saline soaked gauze (avoid repeated ‘looking’ and mini-washouts).
Timing of debridement:
Immediate – highly contaminated (agriculture, aquatic, sewage) or vascular compromise
Within 12 hours – for solitary high energy injuries
Within 24 hours – for all low energy injuries
Definitive soft tissue cover / closure in 72 hours.
Compartment syndrome is defined as a rise in pressure within a fascial compartment causing local tissue ischaemia and hypoxia. This is manifest by a progressive and deteriorating situation. Initially the interstitial pressure of the compartment rises. This causes the thin-walled veins to collapse thus causing venous hypertension. The blood flow out of the compartment is therefore comprised and like a traffic jam it starts to back up as the arterial inflow pressure is still greater than the compartment pressure. With the onset of cellular death, the cell membranes rupture and release osmotically active cellular contents into the interstitial space. This creates an osmotic gradient which draws more fluid into the compartment and hence increases the pressure further. Myonecrosis can occur within 2 hours of onset of ACS and after 6-8 hours irreversible ischaemic damage has occurred. Eventually the pressure is such that the arterial supply is compromised and clinically this is recognised with absent pulses. This is a late stage and should be avoided at all costs.
In this technique I present the case of an open tibial fracture following a crush injury mechanism. A heavy goods vehicle (HGV) axel fell off a stand and trapped the patient’s limb for a few minutes while co-workers struggled to lift it and extricate the patient. Here prophylactic fasciotomies have been performed, as the likelihood of developing an ACS is high.
The fracture has been temporarily stabilised with the Hoffmann 3 External Fixation system. This is a modular, multi-planar external fixation system with independent pin placement capabilities, rapid assembly Snap-Fit couplings and it’s MRI conditional up to 3.0 Tesla. The Hoffmann 3 was developed for use in acute trauma, damage control orthopaedics and definitive fracture fixation. The Delta Couplings are compatible with Hoffmann II and you can use any combination of 5, 8 and 11mm connecting rods.
Readers will also find the following OrthOracle techniques of use:
Fasciotomies of the calf for exertional compartment syndrome
Distal tibial fracture managed with fixator assisted Synthes Expert tibial nail with supra-patella nail approach and blocking screw
Tibial intramedullary nailing (suprapatella approach): Synthes Expert Tibial Nail.
Tibial shaft fracture: Fixation with a Taylor Spatial Frame (TSF) circular external fixator (Smith and Nephew)

INDICATIONS
Forty percent of all trauma related acute compartment syndromes (ACS) occur after fractures of the tibial shaft. The incidence of ACS in tibial fractures is between 1-10%. Risk factors for ACS are: male gender; age < 35 years; open fracture; crush injuries; intramedullary nailing; anticoagulation therapy; high energy and penetrating trauma; vascular injuries; tourniquet use; haemophilia; intravenous or interosseous infusions; drug overdose.
Indications for the use of temporary an external fixator include: open fractures with high levels contamination; open fractures that can not be primarily closed; complex injuries that require further surgical planning; high energy injuries with an evolving soft tissue injury; damage control orthopaedics.
SYMPTOMS & EXAMINATION
The classical symptom in the conscious patient is disproportionate pain. Therefore pain in excess of what you would anticipate and that is not relieved with analgesia should make you consider compartment syndrome. Combining this with the mechanism of injury and other risk factors, you should have a low threshold for suspecting it and should promptly assess and rule it out.
Paraesthesia is sometimes present as the nerves become ischaemic however, the remaining 4Ps of an ischaemic limb are all late findings and should not be referred to in the context of compartment syndrome. They are: Pallor; Paralysis; Pulseless; Poikilothermia (impaired temperature regulation – cold).
When examining a patient with compartment syndrome, they are usually ashen and grey in facial appearance. They are often sweating profusely and look like they are in agony. When passively stretching the muscles of the involved compartment this exacerbates their pain. It should be noted that passively stretching the great toe (dorsiflexion) will only stretch the Flexor Hallucis Longus which is located within the deep posterior compartment, so it is essential that you have a good understanding of the leg anatomy and its’ contents.
The leg has 4 compartments, which are well demonstrated in axial section in the attached BOA guidelines on the management of acute compartment syndrome.
Anterior compartment
Tibialis Anterior; Extensor Hallucis Longus; Extensor Digitorum Longus; Peroneus Tertius
Deep Peroneal Nerve; Anterior Tibial Artery
Lateral compartment
Peroneus Longus; Peroneus Brevis
Superficial Peroneal Nerve, Peroneal Artery
Deep posterior compartment
Tibialis Posterior; Flexor Hallucis Longus; Flexor Digitorum Longus; Popliteus
Tibial Nerve; Posterior Tibial Artery
Superficial posterior compartment
Gastrocnemius; Soleus; Plantaris
Sural Nerve
IMAGING
Imaging is not indicated for acute compartment syndrome as it would cause an unnecessary delay in surgical treatment. If imaging were obtained, then a plain x-ray would usually show a fracture (as ACS is associated with acute skeletal trauma) and the soft tissues would be slightly more radio-dense (appear whiter) as the volume of interstitial fluid has increased. A CT scan may only show swollen compartments but would need a comparison view of the contralateral limb, as there is wide variation in body size and habitus. An MRI scan would have increased signal on T2 weighted images due to the excess fluid within the compartment and this would be outside the primary zone of injury (i.e. not simple oedema related to the injury).
COMPARTMENT PRESSURE MEASUREMENT
Please see the results section of this technique for further information. For acute compartment syndrome, this is usually a clinical diagnosis. Compartment pressure measurement has a role in the unconscious patient, as they cannot report their pain or pain on passive stretch of the compartment contents. If performing a compartment pressure measurement, you should measure it outside the immediate zone of injury, otherwise the reading may be falsely high. Also please remember that each compartment needs to have a separate pressure measurement.
There is a description in the OrthOracle technique Fasciotomies of the calf for exertional compartment syndrome on how to use a compartment pressure measuring device
ALTERNATIVE OPERATIVE TREATMENT
The treatment of acute compartment syndrome is a true orthopaedic surgical emergency and there should be no delay in performing the fasciotomies. This, however, is not always the case and patients with ACS often suffer a delay in diagnosis and treatment. For acute compartment syndrome, I would always use a double incision technique. I feel using a single incision makes full decompression of all compartments less straightforward.
NON-OPERATIVE MANAGEMENT
Non-operative management is generally reserved for chronic exertional compartment syndrome.
Some surgeons, however, will prefer to manage foot ACS without surgery, as the complications from the fasciotomies are often worse than the sequelae of the untreated compartment syndrome.
Initial non-operative treatment would involve administering opiate analgesia, releasing any dressings or casts, and slight elevation of the limb to help facilitate venous drainage. This should be performed in parallel to calling for senior support and arranging an emergency operating theatre.
CONTRAINDICATIONS
The only contraindication for fasciotomy is in the delayed or missed presentation of acute compartment syndrome. If the compartment has necrosed then there is a risk of a reperfusion injury or wound problems such as deep infection / delayed healing. Depending upon its extent radical muscle debridement, or on occasion limb amputation may be required.

The procedure is performed under General anaesthesia.
Intravenous antibiotics are administered at induction (if not already given in the emergency department).
The patient is positioned supine on a radiolucent table.
No tourniquet is used.

The patient is put on bed rest with the limb supported with pillows and slight elevation to facilitate venous drainage.
Post-operative bloods are requested specifically looking for any evidence of rhabdomyolysis and acute kidney injury. In some units daily Creatine Kinase (CK) levels are checked to ensure they are improving.
Antibiotics are given until definitive wound closure / coverage.
The patient is not allowed to bear any weight on this limb.
Definitive coverage is planned for within 72 hours.

Performing fasciotomies within 6 hours of diagnosis is associated with a good outcome (88% good; 3.2% amputation rate) compared to fasciotomy after 12 hours – good outcome only 15% and 14% amputation rate.
Hayakawa H, Aldington DJ, Moore RA. Acute traumatic compartment syndrome: a systematic review of results of fasciotomy. Trauma 2009; 11(1): 5-35.
The delta pressure was proposed by Whitesides et al. as an indicator of ACS. The delta pressure is calculated by measuring the intra-compartmental pressure and subtracting this from the diastolic blood pressure. If the value is greater than 30 mmHg and there is clinical suspicion of ACS then urgent fasciotomy is indicated.
Whitesides TE, Haney TC, Morimoto K, Harada H. Tissue pressure measurements as a determinant for the need of fasciotomy. Clin Orthop Relat Res 1975; 113: 43-51.
McQueen et al. reported data suggesting that continuous pressure monitoring should be the gold standard for diagnosis of ACS; using a threshold for fasciotomy related to the perfusion pressure (intramuscular pressure within 30 mmHg of the diastolic blood pressure for 2 consecutive hours or more), they demonstrated a sensitivity for diagnosis of ACS of 94%.
McQueen MM, Duckworth AD, Aitken SA, Court-Brown CM. The estimated sensitivity and specificity of compartment pressure monitoring for acute compartment syndrome. J Bone Joint Surg Am 2013; 95-A: 673-7.
It should be noted that not all UK hospitals have access to continuous compartment pressure monitoring facilities. Also the majority of surgeons would only use compartment pressure testing in the unconscious patient that is unable to report their level of pain or pain on passive stretch of the compartment contents.
Tornetta et al. recorded pre-operative, intra-operative and post-operative blood pressures and concluded that if you were to use the intra-operative blood pressure for calculation of the perfusion pressure, this could lead to unnecessary fasciotomies as the intra-operative blood pressure is lower. They recommended using pre-operative blood pressures when the patient is under general anaesthesia.
Kakar S, Firoozabadi R, McKean J, Tornetta III P. Diastolic blood pressure in patients with tibia fractures under anaesthesia: implications for the diagnosis of compartment syndrome. J Orthop Trauma 2007; 21: 99-103.
According to the BOAST guideline (diagnosis and management of compartment syndrome of the limbs), if the absolute compartment pressure is greater than 40 mmHg with clinical symptoms of compartment syndrome, then urgent surgical decompression is indicated.
Finally the NHS Litigation Authority settled 48 claims related to compartment syndrome in the years 2008/9 to 2018/19 for a total of £12,239,999.
Majeed H. Litigations in trauma and orthopaedic surgery: analysis and outcomes of medicolegal claims during the last 10 years in the UK National Health Service. EFORT Open Rev 2021; 6: 152-59.
Reference
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