
Learn the Intertrochanteric neck of femur fracture treated with a proximal femoral nail (Synthes long TFNA) surgical technique with step by step instructions on OrthOracle. Our e-learning platform contains high resolution images and a certified CME of the Intertrochanteric neck of femur fracture treated with a proximal femoral nail (Synthes long TFNA) surgical procedure.
Intertrochanteric hip fractures are more commonly treated with a Dynamic Hip Screw (DHS) in the UK. However, there is good reason to consider a nail in certain situations, in particular if there is any lateral wall or greater trochanter compromise. This is because the DHS is designed to allow the fracture to collapse and in the absence of a lateral wall to buttress this collapse, the femoral diaphysis can medialise and the hip abductors lose their mechanical advantage. If recognised, this situation can be prevented by augmenting the DHS with a Trochanteric Stabilisation Plate (TSP). However this often irritates the lateral soft tissues and can cause a trochanteric bursitis.
The National Institute for Health and Care Excellence (NICE), an advisory body in the UK, states that adults with trochanteric fractures above and including the lesser trochanter should be treated with extramedullary implants. Evidence to support their position is that similar clinical outcomes can be achieved with both types of device and there is some evidence for a higher re-operation rate due to periprosthetic fracture with a nail, which is also a more expensive implant than a DHS. Looking outside of the UK, then these fracture patterns are routinely treated with intramedullary devices.
Intramedullary implants have been reported to be associated with a higher 30 day mortality when compared with sliding hip screws and Whitehouse et al. suggest that for every 112 femoral nails there will be 1 excess death. However, they do not know whether the implant / technique is causative or whether there were significant differences between the cohorts, as this was not a randomised controlled trial. It is therefore important to ensure that these devices are used selectively.
The TFNA is available as either a short nail (lengths 170mm, 200mm, 235mm) or a long nail (lengths 300-480mm) and can be used with either a screw or helical blade. The proximal end of the nail is 15.66mm and distally the nails are available in 9mm, 10mm, 11mm, 12mm and 14mm diameters. It has a radius of curvature (ROC) of 1.0 metres which is different to its’ predecessor the PFNA which had a ROC of 1.5 metres. Internally there is a pre-assembled locking mechanism to control the blade rotation and either lock it statically or dynamically. The blade angles are available in 125 degrees, 130 degrees and 135 degrees and all nails have an anatomic 10 degrees of anteversion. The nails are made from titanium and accept 5mm locking bolts distally. In comparison with a competitor nail such as the Stryker Gamma3 nail which has a ROC of 1.5 metres, the TFNA is more likely to have an anatomical fit with the normal anterior bow of the femur and reduces the risk of anterior impingement of the nail in the distal femur which can potentially perforate or cause distal femoral fractures.
Implant failure is a rare event but Synthes has recognised that when these nails do fail, they commonly tend to fail at the screw / blade hole. This can mean that subsequent extraction is difficult. To overcome this there is a thread internally in the nail (below the blade hole) where an instrument can be attached and the nail removed more easily.
The TFNA can be augmented with low viscosity bone cement that can be injected through the cannulated screw or helical blade into the femoral head for patients with severe osteoporosis. To do this, the insertion handle is removed and the 3.2mm guide wire is removed from the screw or blade. The cement is then injected through the cannulation where the wire previously was and exits through perforations in the tip of the screw / blade. Bone cement (polymethylmethacrylate – PMMA) is however contraindicated in the following circumstances:
If there is a risk it will leak into the joint e.g. perforated the head with a guide wire
Intracapsular fractures
Patients with severe cardiac / pulmonary insufficiency
Patients with known allergy to any of the cement components e.g. antibiotics
Whitehouse MR, Berstock JR, Kelly MB, Gregson CL, Judge A, Sayers A, Chesser TJ. Higher 30-day mortality associated with the use of intramedullary nails compared with sliding hip screws for the treatment of trochanteric hip fractures. A prospective national registry study. Bone Joint J. 2019 Jan; 101-B(1): 83-91.
Readers will also find the following OrthOracle operative techniques of interest:
Stryker Omega Dynamic Hip Screw for extra-capsular neck of femur fracture
Femoral intramedullary nail: Synthes Expert Lateral Femoral Nail (LFN) for impending pathological fracture.
Femoral (proximal) intramedullary nail: Synthes Expert Lateral Femoral Nail (LFN)
Fixation of a diaphyseal femoral fracture with a Depuy-Synthes Expert retrograde/antegrade femoral nail (RAFN)
Infected femoral nail removal and debridement with Synthes Reamer Irrigator Aspirator (RIA)

INDICATIONS
The Trochanteric Femoral Nailing Advanced (TFNA) system is indicated for adults (or adolescents with fused growth plates) in the following scenarios:
Stable and unstable pertrochanteric fractures
Intertrochanteric fractures
Basal neck fractures
Combinations of pertrochanteric, intertrochanteric, and basal neck fractures
The long nail is additionally indicated for:
Subtrochanteric fractures
Pertrochanteric fractures associated with diaphyseal fractures
Pathological fractures (including prophylactic use) in both trochanteric and diaphyseal locations
Long subtrochanteric fractures
Proximal or distal non-unions, malunions and revisions
SYMPTOMS & EXAMINATION
Hip / proximal femoral fractures have a classic appearance of a shortened and externally rotated leg. They are usually very painful and the patient is unable to move the leg without considerable discomfort.
In undisplaced or occult fractures, the leg will not be short or externally rotated but patients typically cannot tolerate any weight-bearing or are unable to do a straight leg raise (lift the leg off the examination couch or bed).
The leg should be examined to ascertain the neurovascular status and identify which area to obtain x-rays of, in general though, try not to move the leg more than is absolutely necessary.
IMAGING
A plain AP X-ray pelvis and a lateral hip X-ray are usually sufficient to make the diagnosis.
In occult fractures where the fracture is not obvious on the initial x-rays but is clinically suspected, then a further radiographic view may help make the diagnosis. The patient is positioned supine and 10 degrees of internal rotation is applied to the thigh and a further AP x-ray obtained. By changing the rotation of the leg subtly, it can sometimes reveal the fracture line.
An MRI scan is the investigation of choice to rule out a fracture in patients with localising symptoms but normal X-rays.
In complex injuries CT scans are very helpful to determine the fracture anatomy and help plan the surgery. For example, where the proximal fragment is flexed and has an anterior spike, it is useful to know whether this is still connected to the femoral neck / head. If it is, then I routinely open the fracture to reduce this anterior spike on to the remaining diaphysis. By reducing it early, you then have a better chance of siting the entry wire correctly in the proximal femur. A common mistake is the perception that the nail can be used to reduce a flexed proximal fragment on to the diaphysis. This is a mistake in my view, as the posterior wall is often missing from the proximal fragment and is either a separate fragment or is still attached to the diaphysis. Without the posterior wall on the proximal fragment, there is nothing for the nail to push against to achieve the reduction manoeuvre.
ALTERNATIVE OPERATIVE TREATMENT
A Dynamic Hip Screw (DHS) is the most likely alternative treatment device. In cases with deficient lateral walls or greater trochanters, it may be necessary to augment the device with a trochanteric stabilisation plate.
NON-OPERATIVE MANAGEMENT
Non-operative management is reserved for undisplaced fractures that can tolerate weightbearing or can straight leg raise, in compliant and reliable patients. There is, however, a risk that if such a fracture displaces following a second fall, then the surgery will be more complicated.
Patients considered too high an anaesthetic risk to survive the operation may be treated non-operatively, but mortality is high from the prolonged bed rest and decreased mobility.
CONTRAINDICATIONS
The TFNA is contraindicated for use in pre-existing infection, femoral deformity or intracapsular neck fractures.

The procedure can be performed under either General or Spinal anaesthesia.
Intravenous antibiotics are administered at induction.
The patient is positioned supine on the traction table.
The injured limb is mounted into the traction boot and the contralateral limb is placed into a direct placement leg holder boot.
The contralateral leg is flexed at the hip (approx. 90 degrees); flexed at the knee (approx. 30 degrees – to relax the sciatic nerve); and abducted to allow the C-arm to obtain a lateral view of the injured hip.

The patient requires post-operative bloods to rule out any excessive drop in haemoglobin (Hb) and also to ensure they do not develop an acute kidney injury.
Venous Thrombo-Embolism (VTE) prophylaxis is required for 28 days (according to NICE guidance).
The patient can mobilise Full Weight Bearing (FWB) immediately.
Wounds should be reviewed at 2 weeks and any superficial sutures removed.
X-rays should be performed at 2 weeks and every 6 weeks until fracture union is confirmed.

Schmutz B, Amarathunga J, Kmiec S, Yarlagadda P, Schuetz M. Quatification of cephallomedullary nail fit in the femur using 3D computer modelling: a comparison between 1.0 and 1.5m anterior bow designs. J Orthop Surg Res. 2016 Apr; 11(1): 53
In a study by Schmutz et al. they compared the anatomical fit of 2 antegrade femoral nails using a 3D computer model. The TFN-Advanced (Depuy Synthes) has a radius of curvature (ROC) of 1.0m and the Gamma3 (Stryker) has a ROC of 1.5m. They created 63 3D models (31 Caucasian, 28 Japanese, and 4 Thai). The mean age of the specimens was 77 years (+/- 8.1 years) and the mean height was 158.5cm (+/- 9.6cm). They found that the TFNA protruded by 1.9mm and the Gamma3 by 2.1mm (p=0.007). They concluded that the TFNA resulted in a better fit.
Yuan H, Acklin Y, Varga P et al. A cadaveric biomechanical study comparing the ease of femoral nail insertion: 1.0 vs 1.5m bow designs. Arch Orthop Trauma Surg. 2017 May; 137(5): 663-671.
In a cadaveric study by Yuan et al. they compared the ease of insertion of nails with a 1.0m ROC (TFNA – Depuy Synthes) and a 1.5m ROC (PFNA – Depuy Synthes). They found that compared to PFNA there was a significant decrease in insertion force and nail deformation suggesting that nails with a 1.0m ROC are easier to insert.
Yee DKH, Lau W, Tiu KL et al. Cementation: for better or worse? Interim results of a multi-centre cohort study using a fenestrated spiral blade cephalomedullary device for pertrochanteric fractures in the elderly. Arch Orthop Trauma Surg 2020 Apr 25; online ahead of print.
Yee et al. retrospectively reviewed their patients that were treated with a TFNA and analysed the complication rates of those treated with cement augmentation (CA, 47 patients) of the blade compared with those that did not have cement augmentation (NCA, 29 patients). They found that the rate of fixation failure was 2.1% (CA) vs 13.8% (NCA) p=0.047. There was also no statistically significant differences in either 30 day or 3 month mortality. They conclude that although CA may decrease the risk of fixation failure, the performing surgeon must be capable of dealing with intra-operative complications such as cement leakage into the joint.
Reference
- orthoracle.com