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Proximal Tibial Osteotomy using a Newclip plate

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High tibial osteotomy (HTO) is a well-established and commonly used treatment for younger and active older patients with medial compartment osteoarthritis of the knee and varus malalignment.
The aim of the HTO is to shift the mechanical axis from the medial to the lateral compartment in order to reduce pain and delay the application of a total knee replacement (TKR). The open wedge HTO technique via medial approach was first described by Hernigou et al. in 1987 and has subsequently become the preferred method of correction. Progression of damage to the joint surfaces due to overloading can be significantly retarded by realignment of the extremity with the aim of at least reducing the overload on the medial compartment to a value close to physiological. Further reduction of medial load by making the line of Mikulicz pass far lateral to the intercondylar eminence would only cause the lateral joint to suffer overload while taking the risk of knee knocking during ambulation. The amount of correction (valgisation) to be aimed at is still much debated. Fujisawa et al. reported good results when the Mikulicz line passed through a point between 30% and 40% lateral to the midpoint of the knee (total width of knee being 200%). Based on this, the term “Fujisawa point” has been coined, which is defined as 62% of the entire width, measured from the medial side. We advocate some overcorrection of the varus deformity to a level dependent on the severity of the medial pathology. In instability and the treatment of chondral lesions the correction is to the up slope of the lateral tibial spine. In osteoarthritis the correction is taken further to the tip or downslope of the lateral spine but not beyond the Fujisawa point.

Isolated medial compartment osteoarthritis – this procedure is particularly suited to young adults with symptomatic osteoarthritis. These are the patients in whom it is wise to delay arthroplasty for as long as possible. A group particularly suited are young males who work in heavy labour, e.g. the building trade.
Medial compartment pain and varus alignment in patients with medial overload syndrome. This is usually secondary to medial meniscal deficiency following meniscectomy. The procedure can be combined with meniscal transplant in young patients (<40yrs)
ACL Instability: Correction of varus alignment should be considered in patients with chronic ACL deficiency when the posterolateral structure are elongated and patients present with a varus thrust. HTO should be considered in patients with significant varus prior to revision ACL reconstruction.
PCL instability: HTO should be considered in patients with medial compartment degeneration in association with PCL deficiency. The tibial slope can be increase in conjunction with the coronal alignment in order to correct the tibial sag.
Medial compartment chondral lesion and varus alignment. HTO can be combined with a cartilage repair in order to optimise the biomechanical environment.
Previous failed lateral ligament reconstruction and varus alignment.
Investigations
Weight-bearing x-rays – including long-leg alignment views are vital to assess the appropriateness and the required correction angle. Techniques to plan the osteotomy are well described in publications from the AO group.
MRI – can be of benefit to assess the other compartments of the knee (lateral and patello-femoral) and the integrity of the ligaments
Contraindications:
Smoking
Inflammatory arthritis
Active infection
Widespread osteoarthritis (lateral and patello-femoral compartment)
Fixed flexion deformity >10% is a relative contra-indication bearing in mind that altering the sagittal slope of the osteotomy can improve a small fixed flexion deformity.
Flexion <90degrees
Very large fixed varus deformity – a combined femoral osteotomy needs to be considered in this scenario
BMI >30
Associated conditions that impair bone healing
Alternative treatment options:
Analgesia to control symptoms
Physiotherapy combined with steroid injection
Off-loading knee brace
Arthroplasty

The patient is positioned on a radiolucent table with a tourniquet applied to the operative leg. A side post and foot roll is used so that leg can be positioned at approximately 90 degrees of flexion.
The method of determining the degree of correction needs to be determined prior to surgery. This can be done on the pre-operative long le films, Intra-operatively using a lead or metal rod or using navigation. Latterly patient specific instrumentation has been introduced by a number of companies however this adds additional cost to the procedure. My preference is to measure the correction intra-operatively. This allows for correction of rotational alignment which does affect the mechanical axis. Whilst this method of assessment is non-weigtbearing it is the most reliable in my hands having tried all methods. The equipment needed is:
High thigh tourniquet
Image intensifier – positioned on the ipsilateral side
Radiolucent operating table – preferably with slidable table in oder allow II access to the hip
Side support
Foot roll
Sagittal saw – Approximately 80-90mm long, 0.89mm thick and 20mm wide
2 x 2mm long k-wires
Newclip osteotomy plate
10ml of Demineralised bone matrix

Fluoroscopy is used to place an ECG sticker over the centre of the the hip joint when the rotation of the lower limb is corrected to neutral i.e the foot is pointing upwards.

An ECG sticker is then placed over the centre of the ankle with the foot pointing upwards.

Once the markers are correctly placed, they are secured with the use of tape. A wire can then be used to determine if the mechanical axis (MA) on table correlates with that of the alignment films.

If the MA does not correlate with the alignment films and is in fact neutral then a decision regarding whether to proceed needs to be made.

The leg is prepared with alcoholic betadine and then prepped and drapes in the usual manor for a knee arthroscopy. A clear bag is place over the foot so as to ensure the ECG sticker placed over the centre of the ankle is clearly visible. A diagnostic knee arthroscopy is then undertaken to confirm the pathology. It is important to confirm that the lateral compartment and the patellofemoral joint are structurally intact and therefore it is safe to proceed with HTO. Any medial meniscal pathology can be addressed at this time.

A transverse incision is made just above the level of the pes. This can be identified by simple palpation of the hamstring tendon insertion. Full thickness skin flaps are created superiorly and inferiorly so that the plate will fit comfortably.

The knee is then extended and the dissection is continued anteriorly to the anterior aspect of the tibial tubercle. The patella tendon is identified and the medial margin is incised.

A hohmann retractor is then inserted under the tendon and the fat cleared so that the tendon insertion point can be clearly identified.

A sagittal saw is then used to undertake an oblique osteotomy of the tibial tubercle at an angle of approximately 60 degrees extending from just superior to the patella tendon, posteriorly to a point approximately 1/3 of the AP width of the tibia, ensuring to pass through 2 corticies. The patella tendon must be protected by the hohmann retractor at all times. The saw should not penetrate too laterally in order to avoid tibialis anterior muscle injury with the saw.
The facia above the hamstring tendons is then incised and the MCL is generously released from the tibia using a periosteal elevator. It should be released enough so that a Hohmann retractor can be easily placed under the MCL and posterior tibia.

The proposed vertical osteotomy site is then drawn out with the diathermy on the tibia. This is usually just above the level of the pes and should extend over the remaining 2/3 of the thickness of the tibia. The veritical osteotomy should meet with the previously made tubercle osteotomy.
Two long 2mm k-wires are inserted under Image intensifier extending from the proposed osteotomy site obliquely across the tibia.

The tip of the wire should end just below the tip of the fibula head and short of the lateral cortex. The first wire is inserted posteriorly

A second parallel wire is inserted anteriorly.

The wires should overlap when viewed on the image intensifier.

With the posterior hohmann retractor in place a sagittal saw is used to complete the vertical osteotomy cut. The saw blade is kept against the inferior surface of the previously placed wires in order to ensure accurate osteotomy. It is important to ensure that the posterior cortex is cut with the saw so that the osteotomy hinge is anteriorly based. This will ensure there is minimal change to the posterior tibial slope.

The vertical osteotomy is carried under under II to ensure the saw bladé stays close to the inferior surface of the previously inserted wires. The saw blade should stop 1cm short of the lateral cortex of the tibia.

Stacking osteotomes are then used to complete the osteotomy and achieve initial gap opening. The largest osteotome is placed first so that the lip of the osteotome faces inferiorly. The osteotome is placed inferorly in an attempt to ensure the posterior cortex has been completed. If the posterior cortex has been completed this should go easily.

II is used to ensure the osteotome follows the inferior surface of the wires and stops 5-10mm short of the lateral tibial cortex.

The second osteotome is then inserted between the first osteotome and the wires.

The second osteotome should be inserted so that its tip is longer than that of the first. This will protect the articular surface from fracture.
During insertion of the second osteotome, a change in the varus tibial slope should be noted. If the slope does not become more valgus as the osteotome is inserted then one should ensure that the posterior cortex has been fully divided. If the cortex is not fully divided then the bone will be compressed rather than the osteotomy distracted.

A 3rd osteotome in then inserted in order to plastically deform the lateral cortex.
The osteotomes are then removed. The assistant should place their hand under the knee in order to prevent hyperextension, which can cause hinge fracture. It is better to use only 3 osteotomes in order to prevent over tensioning the MCL and thus hinge fracture. Often the tendency is to under release the MCL during the initial exposure.

A laminar spreader with a wheel should be inserted as posteriorly as possible into the osteotomy gap in order to prevent slope change.
By pulling on the wires and stabilising the ankle, the osteotomy gap can be opened sufficiently to allow the spreader to be inserted easily. If the gap does not open easily the the MCL needs to be released further.

The gap is then increased gradually until the tibial slope is reversed so that it is neutral or a few degrees valgus. The laminar spreader can also be used to assess the sufficiency of the MCL release. If opening the ostetomy gap becomes difficult i.e requires significant pressure on the spreader, further MCL release needs to be carried out. This is done with a 15 blade between the arms of the spreader using a pepper-pot technique.
If during this stage a hinge fracture is identified/sustained then I usually change the plate to the larger 4 hole plate in order to place an initial compression screw distally, which allows reduction of the usual tibial translation seen. Normally it is still possible to achieve the desired correction with a hinge fracture as the translation is usually minimal, however if the translation prevents sufficient opening of the osteotomy then a second lateral incision will need to made. The area of the hinge fracture is exposed and the fracture reduced with either a step staple or a semi-tubular plate. This will then allow the osteotomy gap to be opened to the desired degree.

The newclip plate (with the anterior and posterior proximal tubes attached) is then inserted into the wound and moved proximally. The plate should sit anteriorly on the tibia.

An initial wire is inserted in the anterior tube in order gauge appropriate placement of the plate.

The satisfactory position of the plate and the proposed screw location is confirmed using the image intensifier.

Once happy, the posterior tube is drilled to achieve a bi-cortical hold. This screw is usually 45-50mm in length.

The wire is removed and prior to drilling the anterior tube one needs to ensure that the distal plate is in the middle of the tibia. The anterior screw should be as long as possible, the maximum length with this system is 70mm.
The middle screw is then drilled, it is poly-axial and needs to be placed between the anterior and posterior screws (in the vertical plane) in order to distribute the forces. Again, the angle of insertion in the horizontal plane should be in such a way to ensure the maximum screw length possible.

The mechanical axis is then re-measured and the correction assessed by stretching the diathermy lead between the previously placed ECG stickers which can be palpated through the drapes. The laminar release is opened or closed dependent of the desired correction.

The most proximal hole distal to the osteotomy is then drilled, tapped and a locking screw inserted.

Once the most proximal screw has been inserted the osteotomy gap will be fixed allowing removal of the laminar spreader. This will allow easier access to the distal 2 screws in the plate through the transverse incision. The distal screw holes are drilled in a bi-cortical fashion. Prior to screw insertion the screw hole needs to be tapped to allow full seating of the screw in the harder cortical bone.
If the distal screw holes cannot be reached through the transverse insertion then a separate percutaneous incision can be made.

10mls of Demineralised Bone Matrix is then inserted into the osteotomy gap in order to reduce potential swelling.

A final AP radiograph is undertaken to the final construct is satisfactory.

A large drape is then placed on the contralateral aspect of the table to allow the image intensifier to pass underneath the table and take a true lateral radiograph.

Skin clips are usually then for the skin.

The wound is dressed with a simple opsite dressing and a wool and crape bandage.

The wound is then closed in layers. A 2.0 Biosyn in used for the fat

Patients are encouraged to flex as pain allows. Return of range of motion is desirable as soon as possible post-surgery.
Patients remain partial weightbearing for 2 weeks post surgery and then commence full weightbearing as pain allows.
Two further doses of antibiotics are prescribed and clips are removed 14 days post surgery.
No chemical thromboprophalaxis is prescribed but TED stockings are worn for 6 weeks.
Anti inflammatories are discontinued 2 weeks post-surgery
An x-ray is taken at 6 weeks and then every 3 months until union is achieved.
No splint or brace is prescribed
The plate does not have to be removed and can be left in situ if a symptomatic. As a general rule I remove all plates at the patients convenience once union has been achieved.


Ten-year survival rates for closed wedge osteotomy were reported from 51% by Naudie et al to 93.2% by Koshino et al (25, 34, 51, 59). The best results by Koshino was related to some post operation factors including no flexion contracture, valgus anatomical angle of 10°, and concomitant patellofemoral decompression procedure if indicated (96). Coventry et al also reported a 10 year delay in total knee arthroplasty in 75% of patients if overcorrection to at least 8° of valgus was achieved (34). Studies on MOWHTO showed a 10-year delay in arthroplasty in 63% of 73 patients (97), and 85% of 203 patients. Schallberger et al followed 54 patients with isolated medial compartment OA for a median of 16.5 years that were treated by either MOWHTO or lateral closing wedge osteotomy, and found 24% conversion to total knee arthroplasty.
1. Brinkman J-M, Lobenhoffer P, Agneskirchner JD, Staubli AE, Wymega AB, Heerwarden RJ. Osteotomies around the knee. J Bone Joint Surg Br. 2008;90-B:1548–1557
2. Fujisawa Y, Masuhara K, Shiomio S. The effect of high tibial osteotomy on osteoarthritis of the knee. An arthroscopic stuy of 54 knee joints. Orthop Clin North Am.
3. Return to sports and quality of life after high tibial osteotomy in patients under 60 years of age. Bastard C, Mirouse G, Potage D, Silbert H, Roubineau F, Hernigou P, Flouzat-Lachaniette CH. Orthop Traumatol Surg Res. 2017 Dec;103(8):1189-1191
4.Survival of opening versus closing wedge high tibial osteotomy: A meta-analysis.Kim JH, Kim HJ, Lee DH. Sci Rep. 2017 Aug 4;7(1):7296
5. Patella height is not altered by descending medial open-wedge high tibial osteotomy (HTO) compared to ascending HTO. Krause M, Drenck TC, Korthaus A, Preiss A, Frosch KH, Akoto R.Knee Surg Sports Traumatol Arthrosc. 2017 Apr 17. doi: 10.1007/s00167-017-4548-0. [Epub ahead of print]


Reference

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