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An elbow replacement is an attractive proposition to improve pain in patients that have painful arthritic joints, particularly when compared to the alternatives.
Initial prostheses were fixed hinges (allowing only flexion and extension) which, due to the normal varus and valgus toggle of the ulna in relation to the humerus at the joint, led to predictable early loosening of the components. Unlinked components (with the humeral and the forearm components not being physically connected and relying on balancing the soft tissues for stability) were developed, but these were prone to dislocation.
Contemporary implants are therefore usually coupled (physically connected together), but with play in varus and valgus replicating the normal joint to reduce the likelihood of mechanical loosening. Nonetheless, loosening of the components (usually aseptic, but potentially secondary to infection) still frequently occurs, and therefore patients are recommended to restrict activities following elbow replacement for the remainder of their lives, in particular limiting lifting loads and torsion activities. For this reason, the number of patients who will accept the required lifestyle restrictions needed for a replacement to so stand to benefit from elbow replacement after appropriate counselling are relatively limited.
Patients with inflammatory arthritis have generally been the main group of patients who underwent elbow replacement surgery, in large part as their functional demands have tended to be lower due to the involvement of multiple other joints with their disease. With the advent of biologic treatments for systemic inflammatory arthropathies, the number of patients who need to consider having an elbow replacement has reduced. As the number of patients receiving elbow replacements for inflammatory arthritis has reduced, the proportion of patients receiving implantations for un-reconstructible trauma in the elderly, , has increased. The outcomes reported in this group has been good, at least in the medium term. The overall number of primary implantations entered into the UK National Joint Registry each year since data recording began (1st April 2012) has remained around 600 across England and Wales. Most patients having their elbow replaced are still those with an underlying inflammatory arthritis, ideally in their 60’s or older (to minimise the risk of revision surgery being necessary), but if younger patients understand the potential implications of a replacement and accept the restrictions still needed to maximise the longevity of the implant, elbow replacement can be offered to younger patients as well.
The Coonrad-Morrey total elbow replacement is the international market leading elbow replacement implant, used in its current form for around 20 years, with 10-year survivorship of 80-92% reported. In common with most elbow replacements, it is designed for cemented implantation. It represents a reliable, relatively straightforward component to insert with readily available exchange of the polyethylene bearings in the event of significant wear, in the presence of stable implants. The different component sizes have had interchangeable bearings since the early 2000’s to facilitate this.
Newer implants, such as the Latitude EV (Wright Medical), Discovery (Lima) and Nexel (Zimmer-Biomet), are available and are defining their roles in elbow replacement surgery. All have anterior flanges to the humeral component. The Latitude EV can be used as a hemiarthroplasty for treating distal humeral fractures, or as a total elbow replacement, and also has a radial head component. The Latitude also has the option of being inserted coupled (linked)or uncoupled (no linkage between the ulnar and humeral components, which may potentially reduce aseptic loosening), or can even be unlinked at a subsequent procedure once soft-tissue healing has provided stability (or, conversely, be coupled to restore stability if initially inserted unlinked).
The newer implants have advantages in certain technical areas such as easier independent insertion of the ulna and humeral components and where indicated, a radial head component. Whilst the ability to couple the implant once the cemented components are stable may have a theoretical advantages in terms of longevity, none of the newer implants have the data to support a comparable longevity to the Coonrad-Morrey implant. and the surgical techniques and instrumentation are a bit more involved and technically demanding.
I still use the Coonrad-Morrey for most primary replacements, in part due to familiarity, both my own and, as importantly, the theatre staffs. Total elbow replacement even in specialist centres is relatively infrequently performed, the scrub staff will have only a limited exposure to the procedure and the instrumentation. I think under such circumstances it is important to consistently use an appropriate implant, amongst a number of reasons so that the whole team become familiar with the steps and instruments to speed up and improve the operative procedures.
Until more contemporary implants demonstrate a definite survival advantage I will continue to use the Coonrad-Morrey for the majority of my patients, reserving use of a newer implants for younger patients and those in whom I think it is more likely that a revision will become necessary.

INDICATIONS
Painful elbow arthritis:– elbow replacements will more reliably improve pain than improve motion, so pain is still the primary indication for elbow replacement surgery. With the reduction in destructive elbow arthritis since the widespread use of biologic agents to treat systemic inflammatory arthropathies, the number of elbow replacement for arthritis has reduced.
Acute trauma:– elbow replacement is increasingly being used to salvage complex distal humeral fractures in elderly patients where either or both of the fracture pattern and the poor bone quality in osteoporotic patients means that fracture fixation that is sufficiently reliable to permit early active motion could not be reliably achieved, so permitting early rehabilitation and restoration of function in patients who would otherwise probably have a poor outcome from treatment of their fracture.
Osteoarthritis:– non-inflammatory arthritis to the extent that elbow replacement surgery is requested is fortunately uncommon, as patients with isolated arthritis in their elbow will be less likely to accept the functional restrictions that a replaced elbow will require them to observe in order to minimise the risk of early implant loosening.
Haemophiliac arthropathy:– replacement for arthritis due to recurrent bleeding is also fortunately becoming less common with better control of individuals’ clotting disorder.
Post-traumatic reconstruction:– elbow replacement is used as a salvage option for intra-articular and low metaphyseal non-unions and for post-traumatic arthritis, although the clinical outcomes seen are generally inferior to those for inflammatory arthritis, and the rate of post-operative complications, including loosening, are generally higher.
Instability of an arthritic elbow:– a flail elbow can have good function restored by use of a linked prosthesis, but in the absence of significant arthritis, the potential for implant loosening and wear needs to be considered carefully before proceeding with arthroplasty to restore stability.
SYMPTOMS & EXAMINATION
Pain:- diffuse joint pain, worse on motion. Lateral column pain may be from the radiocapitellar joint, and medial pain radiating to the forearm and hand may be arising from the ulnar nerve.
Stiffness:– try to distinguish painful motion restriction from bony impingement (pain at the same side of the joint as the motion has been into- i.e., posterior pain with extension, anterior pain with flexion) from capsular pain (pain at the opposite side of the joint from the direction of motion is a problem due to tension in a tight capsule, i.e., anterior pain when loading the arm in extension). Clinicians are often quick to look for potential osteophyte impingement as an explanation for restricted motion, and tend to overlook the common tether of a tight capsule as a significant contributor to motion loss. Remember to assess (and record) the range of forearm rotation as well as elbow flexion and extension.
Locking:– true mechanical locking from a loose osteochondral body gives rise to brief periods of jamming of the joint. Synovial pinching, potentially with small bleeds into the joint, causes longer periods of motion restriction and associated pain. The response to a diagnostic and therapeutic trial of a corticosteroid injection (CSI) into the elbow can help to distinguish between these two conditions.
Ulnar neuritis:– bulging of a synovitis capsule with an elbow effusion into the floor of the cubital tunnel can cause irritation of the ulnar nerve. Remember to assess the ulnar nerve both for signs of local irritability, and for neurological loss in the hand.
IMAGING AND OTHER INVESTIGATIONS
Plain films:- a destructive arthropathy is usually seen. Depending on the pattern of arthritis, and the distribution of symptoms, replacement may not be the only or even the best option for some patients. Remember that the present of joint degeneration on a plain film does not necessarily mean that the symptoms are due to the arthritis that has been seen.
Cross-sectional imaging can be helpful in some cases, but is often not necessary. CT scans are useful when there has been a history of fracture with the potential for non- or mal-union, or if there is significant malalignment at the elbow, and MRI may be helpful if there is concern about the potential for active or indolent infection.
Neurophysiological assessment is important if there is any concern about the potential for ulnar nerve compromise, if only to act as a baseline for future investigations.
ALTERNATIVE OPERATIVE TREATMENT
For patients with less intrusive symptoms, CSI (corticosteriod injection)into the joint may be sufficient; this can easily be administered using landmark guidance into the soft spot at the confluence of the radiocapitellar and the lateral ulnohumeral joint.
For patients who see good but only brief responses to intra-articular CSI, an arthroscopic debridement procedure may be helpful; this consists of a synovectomy, removal of any loose bodies and, if motion restriction, impingement-pattern pain at the end of range of motion is present, capsulectomy (which can be undertaken as an open or an arthroscopic procedure).
For patients with mechanical locking, arthroscopic removal of any loose bodies is very helpful.
For patients with predominantly lateral column pain that is reproduced by rotating the forearm especially with a clenched fist (“grip and grind” test), radial head excision and synovectomy is still a good potential option.
For patients whose main problem is stiffness, rather than pain, consider arthrolysis. This can be performed open or arthroscopically. In my hands, open surgery will more reliably restore maximum motion, but with a slower recovery process. If flexion is going to be improved significantly, or if the ulnar nerve is clinically irritable, ulnar nerve decompression should be undertaken at the same time).
For younger patients, or those who cannot or will not be able to comply with the recommended post-operative functional restrictions, interposition arthroplasty (arthrolysis with interposition of fascia or allograft tendon) remains a potential option.
NON-OPERATIVE MANAGEMENT
Other than sensible review of analgesic options, lifestyle modifications, and potentially CSI, there are few alternatives for patients with intrusive elbow arthritis.
CONTRAINDICATIONS
Active infection, Charcot arthropathy, and an unwillingness / inability to restrict post-operative use of the arm are all absolute or strong relative contraindications to elbow replacement surgery.
A past history of infection is a relative contraindication.


I ask for the operated limb to be elevated on pillows to keep the hand from being dependent in recovery and when the patient is in bed.
I have routine bloods (FBC/U&E) checked on the 1st post-operative day; despite the patients frequently having co-morbid conditions, it is unusual to need to perform blood transfusions after uncomplicated primary total elbow replacements in my experience.
I ask for AP and lateral plain films to be obtained as soon as comfort allows, to ensure the component alignment and coupling is satisfactory, and that there is no significant residual extruded cement near the articulation.
To protect the triceps repair, I ask for active extension to be avoided for 6 weeks, and then resistance gradually to be re-introduced; I am happy for active elbow flexion, forearm rotation and hand and wrist motion to commence as pain allows.
I ask patients to be instructed in scapular setting exercises as use of a sling tends to promote protraction of the shoulder.
Patients are usually in hospital for one or two post-operative nights.
Before they leave, patients are instructed to seek hospital review before any antibiotics are taken in the event of post-operative wound problems arising; this is to allow wound excision, deep debridement and sampling and exchange of the polyethylene and assembly mechanism in the event of potential infection in order to accurately identify any causative organism and determine optimal antibiotic treatments (part of a Debridement, Antibiotics and Implant Retention, or DAIR procedure).
I review patients’ wounds after 3 weeks, and have them seen at 6-8 weeks to start extensor strengthening.
Patients can resume driving at 6-8 weeks assuming they could safely control a steering wheel in the event of an emergency.
As part of the pre-operative counselling process, patients are advised to avoid lifting more than 500g for the 1st 3 months (a bag of sugar), and more than 2kg lifelong (a 2-litre drink bottle), refraining from activities that would apply torque loads to the elbow; this is re-iterated at all follow-up attendances.
As total elbow replacement is a low-volume procedure, I prefer to keep patients under long-term radiographic surveillance; I have them seen at 6 and 12 months, then annually to 5 years, then bi-annually with imaging (although I would not chase follow-up after 5 years in the event of non-attendance , assuming no problems at the time of the last assessment). I expect all patients to be asked to allow their data to be submitted to the UK National Joint Registry.

Most patients are very happy with the level of pain improvement provided by an uncomplicated total elbow replacement; patients on average gain an additional 26 degrees to their arc of flexion/extension (more extension than flexion), and reliably have stability restored to the joint unless significant loosening or implant dis-assembly should arise.
Aseptic loosening is a problem with elbow replacement surgery, and this is why functional restrictions are required.
Revision surgery is often very challenging, with an increased risk of infection and neurovascular injury; analysis of HES data has shown that patients who require surgical attention to their replaced elbow will have a 30-40% likelihood of needing a further procedure after every successive elbow operation. Bone stock loss through loosening and in the course of removal of components can cause big problems when trying to reconstruct the joint.
Revision of the replacement is needed in approximately 15% of cases within 10 years.
If the problem of aseptic loosening can be successfully addressed, elbow replacement will become a more widely-used technique for patients with painful osteoarthritis and post-traumatic arthritis.
The literature surrounding elbow replacement surgery is limited compared to hip, knee or shoulder replacements, particularly when considering contemporarily-available component systems.
A systematic review I wrote with Andy Carr and Alastair Graham (Little CP, Graham AJ, Carr AJ. Total elbow arthroplasty a systemic review of the literature in the English language up until the end of 2003. J Bone Joint Surg Br. 2005;87:437–44 doi:10.1302/0301-620X.87B4.15692) identified that the published outcomes following surgery using either a linked (sloppy hinge) or an unlinked device were similar, with loosening being the most common mode of failure for both classes (with higher rates of radiographic loosening reported in unlinked than linked devices- 10% vs. 5% at five years), linked replacements restoring a slightly better arc of flexion and possibly better functional results, an approach using a triceps turndown or keeping the triceps in continuity had a lower likelihood of triceps failure than sub-periosteal dissection from the ulna (with post-operative immobilisation not influencing the risk of triceps failure), and the overall reported rate of deep infection was around 4%, and of ulnar nerve palsy 5%.
A more recent systematic review by Welsink et al (2017) (JBJS REVIEWS 2017;5(7):e4 · http://dx.doi.org/10.2106/JBJS.RVW.16.00089) considered articles published from January 2003 to September 2015. They found that formal survival analysis using Kaplan-Meier techniques was more widely used (34/73 papers), that the overall reported survivorship was around 79% at 11.1 years, with little data to support used of one component over another. In terms of reported complications, they noted a deep infection rate of 3.4%, ulnar nerve lesion of 3%, and loosening of 7%. They observed that the majority of the published studies were retrospective case series of a single component (1 RTC; 5 prospective case series).
With Andy Carr and others, I published in 2005 a prospective comparative cohort series comparing outcomes of the Souter-Strathclyde, the Kudo, and the Coonrad-Morrey implants (Little, Graham, Karatzas et al JBJS 87(A): 2439-2448) doi: 10.2106/JBJS.D.02927); we found similar clinical outcomes in terms of range of motion and complications with the three components, but slightly better survival for the Coonrad-Morrey (Kaplan-Meier technique); we did however note focal osteolysis around the ulnar component in 16%. [The ulnar osteolysis was thought potentially to be related to the coating around the proximal ulna used at the time, which has subsequently been changed.]
Kamineni & Morrey published the outcomes of using the Coonrad-Morrey replacement for acute trauma in 49 patients followed for a mean of 7 years (Distal humeral fractures treated with noncustom total elbow replacement J Bone Joint Surg Am, 86 (2004), pp. 940-947), reporting good clinical outcomes with intermediate follow-up, but a 10% revision rate.
Reference
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